November 1, 2012
…research in developing green fluorescent proteins derived from a bioluminescent jellyfish. Much of the acclaim that followed celebrated the novel possibilities of being able to use these glowing molecules to peer inside living cells or whole animals, to observe interactive biology in real time and to ask and do things…
October 9, 2014
…technique to the green fluorescent protein (GFP) that has proven to be such a valuable tool in elucidating biological phenomena. This is the same GFP for which Tsien was awarded the Nobel Prize.” Continetti remembers that Moerner also collaborated with former UC San Diego professor “and organic chemist Jay Siegel…
August 30, 2017
…tadpoles studied with a fluorescent inhibitor of gene [removed]white color beneath the eye in the bottom two tadpoles). In a series of neurobiological studies stretching back eight years, the researchers examined larval frogs (tadpoles), which are known to swim with family members in clusters. Focusing the studies on familial olfactory…
February 22, 2018
…the prey a green fluorescent protein so that he could tell them apart in live-action movies. The “predator” bacteria did kill the E. coli as expected—but they also started glowing green! The cells in this video are growing inside a microfluidic chip—a microscopic chamber with a channel beneath it to…
April 19, 2018
…and vegetables to compact fluorescent light bulbs—can be traced back to UC. Locally, UC San Diego is the largest employer in the city, and more than 1,000 companies have been launched by or use technology produced on campus. Opportunities abound for faculty and students to turn their big ideas into…
May 17, 2018
…wait several minutes, add fluorescent labels and look at the results under a microscope. If a blood sample tests positive for pancreatic cancer, bright fluorescent circles will appear. Lab setup used to test blood samples “This test could be used as a primary screening strategy to identify patients who would…
December 6, 2018
…of DNA encoding green fluorescent protein (GFP), minerals from clay and precursors for acrylic plastic. Then, using ultraviolet light and chemicals, they triggered the formation of a spongy membrane around each droplet, while the DNA within each droplet condensed into a gel-like substance to create a neo-nucleus. The researchers also…
October 17, 2019
…advances such as using fluorescent imaging to more accurately remove cancerous cells; using tissue engineering to repair spinal cord damage; and creating wearable technology to monitor blood pressure. Bridging engineering and medicine might seem commonsense now, but at the time it was a revolutionary idea. He was also the founding…
June 4, 2020
…and give off a fluorescent signal that would then be used to assess patient health. Govil led a team of 11 undergraduates as part of an independent research team in the School of Medicine and together, they built a set of unique machine learning algorithms to identify the biomarkers for…
November 12, 2020
…and application of green fluorescent protein (GFP), which allows some jellyfish to glow. While colleagues discovered and isolated the GFP gene, Tsien found ways to tweak its makeup, making it glow more brightly and consistently. Then, he created a full color palette of fluorescent proteins that scientists could use to…
