Post-COVID Lung Disease Shares Origins with Other Scarring Lung Disorders
July 20, 2022
UC San Diego researchers provide first insights into the fundamental cellular pathologies that drive interstitial lung disease in patients post-COVID.
Your search for “Pradipta Ghosh” returned 28 results
Protein that Keeps Immune System from Freaking Out Could Form Basis for New Therapeutics
October 14, 2020
Treatment with a peptide that mimics the naturally occurring protein GIV prevents immune overreaction and supports a mechanism critical for survival in mouse models of sepsis and colitis, according to a UC San Diego study.
How to Reset a Diseased Cell
May 1, 2015
In proof-of-concept experiments, researchers at University of California, San Diego School of Medicine demonstrate the ability to tune medically relevant cell behaviors by manipulating a key hub in cell communication networks. The manipulation of this communication node, reported in this week’s issue of Proceedings of the National Academy of Sciences,…
Protein That Protects During Stress Sheds Light on How Diabetes Drug Prevents Tumors
November 21, 2016
Researchers at University of California San Diego School of Medicine have identified a previously unknown mechanism that helps fortify the structure and tight junctions between epithelial cells — a basic cell type that lines various body cavities and organs throughout the body, forming a protective barrier against toxins, pathogens and…
Jekyll and Hyde and Seek
February 27, 2018
Writing in the February 27 online issue of Science Signaling, researchers at University of California San Diego School of Medicine and Moores Cancer Center describe how a signaling protein that normally suppresses tumors can be manipulated (or re-programmed) by growth factors, turning it into a driver of malignant growth and…
Genetic Variation Explains Racial Disparity in Esophageal Cancer Cases
September 22, 2022
Researchers at UC San Diego have used artificial intelligence-guided tools to pinpoint both a specific type of immune cell as the driver of esophageal cancer and a specific genetic variation that acts as a protective factor in African Americans.
Girdin One’s Loins
August 19, 2021
UC San Diego researchers detail how a ubiquitous signaling molecule plays a critical role in male fertility, orchestrating key steps that promote sperm motility, survival and fertilization success.
Protein’s Impact on Colorectal Cancer is Dappled
June 30, 2015
Researchers at University of California, San Diego School of Medicine have discovered a cell signaling pathway that appears to exert some control over initiation and progression of colorectal cancer, the third leading cause of cancer-related death in the United States. A key protein in the pathway also appears to be…
Study: E-Cigarettes Trigger Inflammation in the Gut
January 7, 2021
Chemicals used for vaping break down zipper-like junctions between cells in the gut, leading to chronic inflammation and potential for other health concerns.
Artificial Intelligence Could Be New Blueprint for Precision Drug Discovery
July 12, 2021
Researchers at University of California San Diego School of Medicine describe a new approach that uses machine learning to hunt for disease targets and then predicts whether a drug is likely to receive FDA approval.
