February 8, 2016
…has 3D-printed a tissue that closely mimics the human liver’s sophisticated structure and function. The new model could be used for patient-specific drug screening and disease modeling. Researchers said the advance could help pharmaceutical companies save time and money when developing new drugs.
November 14, 2017
Primary liver cancer is now the second leading cause of cancer-related death worldwide, and its incidences and mortality are increasing rapidly in the United Stated. In late stages of the malignancy, there are no effective treatments or drugs. However, an unexpected finding made by a team of University of California…
September 3, 2020
UC San Diego Health is the first hospital in San Diego and only health care system in Southern California to transplant a liver from a donor with Human Immunodeficiency Virus (HIV) into an HIV-positive recipient. The surgery is part of a national clinical trial.
August 23, 2023
With funding from The Leona M. and Harry B. Helmsley Charitable Trust, Jeremy Pettus, MD, an associate professor of medicine and board-certified endocrinologist who specializes in treating diabetes at UC San Diego Health, is leading a study on Liver Targeted Insulin (LTI) in Type 1 diabetes.
November 1, 2022
New study identifies that first-degree relatives of patients with nonalcoholic fatty liver disease with advanced fibrosis (scarring of the liver) are at a 15% risk of developing the condition.
May 14, 2019
Exposure to glyphosate, the primary ingredient in the popular weed killer Roundup, correlates to more severe cases of nonalcoholic fatty liver disease.
February 5, 2015
…million children in the United States have nonalcoholic fatty liver disease (NAFLD), yet most cases go undiagnosed. To help address this issue, researchers at UC San Diego School of Medicine have developed a new magnetic resonance imaging (MRI)-based technique to help clinicians and researchers better detect and evaluate NAFLD in…
March 13, 2019
New preclinical data from University of California San Diego School of Medicine and Moores Cancer Center offers proof-of-principle for a combination immunotherapy that suppresses tumor growth in the liver. Current therapies for liver cancer are largely ineffective, resulting in poor outcomes.
March 18, 2020
New study finds gene therapy improved cardiac, muscle and liver function in Danon disease mouse models.
September 13, 2018
…driver of non-alcoholic steatohepatitis (NASH), a chronic and aggressive liver condition. By identifying caspase-2’s critical role, they believe an inhibitor of this enzyme could provide an effective way to stop the pathogenic progression that leads to NASH — and possibly even reverse early symptoms.
