December 28, 2022
UC San Diego study reveals critical insights into the complex biology of tissue-specific T cells, paving the way for a new branch of precision therapeutics in immunity, autoimmunity, and cancer.
November 21, 2017
…in the Section of Cell and Developmental Biology have “got mail”—of the cellular sort. They know that cells have elaborate “addressing” functions that “send” proteins to the correct compartment, but they are now learning how cells “’write” the addresses and then “read” them. This is important because cellular function depends…
December 11, 2017
…that is key to the development of killer T cells—immune cells important for fighting infections and cancer. The researchers believe Runx3, if properly directed, could be combined with other approaches to help T cells recognize and destroy tumor cells and enhance vaccine efficacy.
November 26, 2014
…embryos are contemplating their cellular fates in the earliest stages after fertilization when the embryo has only two to four cells, a discovery that could upend the scientific consensus about when embryonic cells begin differentiating into cell types. Their research, which used single-cell RNA sequencing to look at every gene…
May 5, 2015
Human pluripotent stem cells possess the ability to grow into almost any kind of cell, which has made them dynamic tools for studying early human development and disease, but much depends upon what they grow up in. Writing in the May 4 online issue of the journal Scientific Reports, researchers…
April 13, 2017
Chinese hamster ovary (CHO) cells are the workhorses behind more than half of the top-selling biologics on the market today. Humira, Avastin and Rituxan are a few. Researchers at the UC San Diego CHO Systems Biology Center are developing new tools, such as genome-scale metabolic models, to optimize CHO cell…
July 31, 2013
A biology and physics professor at UC San Diego has received a $1.15 million grant from the National Science Foundation to establish a series of annual “boot camps” that will educate San Diego-area high school and college students about an emerging field at the intersection of physics and biology called…
August 13, 2014
Our immune system copes with a multitude of threats using a mix-and-match system to create millions of different antibodies.
July 28, 2022
…compartments for an artificial cell.” “I congratulate Neal on this remarkable recognition from the Department of Defense,” said UC San Diego Chancellor Pradeep K. Khosla. “As a research-focused university, this fellowship is not only a testament to Neal’s excellent work, but also a testament to the work our outstanding faculty…
October 15, 2019
UC San Diego bioengineers are a step closer to making CAR T-cell therapy safer, more precise and easy to control. They developed a system that allows them to select where and when CAR T cells get turned on so that they destroy cancer cells without harming normal cells.
