March 6, 2020
A team of chemists and biochemists at UC San Diego used a combination of computational simulations and experiments to deepen understanding of the latest genome editing technology.
March 26, 2024
While CRISPR has shown immense promise as a next-generation therapeutic tool, the gene editing technology’s edits are still imperfect. Researchers have developed a new genetic system to test and analyze CRISPR-based DNA repair and related risks from unintended but harmful “bystander” edits.
February 6, 2014
An international team of researchers, led by scientists from the University of California, San Diego School of Medicine and Indiana University, have identified a protein that broadly regulates how genetic information transcribed from DNA to messenger RNA (mRNA) is processed and ultimately translated into the myriad of proteins necessary for…
February 10, 2022
New research led by bioengineers at the University of California San Diego could make it much simpler to repair disease-causing mutations in RNA without compromising precision or efficiency. The new RNA editing technology holds promise as a gene therapy for treating genetic diseases.
November 16, 2015
…any organism. CRISPR/Cas9 gene editing activity runs continuously, though, leading to risk of additional editing at unwanted sites. Now, researchers at University of California, San Diego School of Medicine, Ludwig Cancer Research and Isis Pharmaceuticals demonstrate a commercially feasible way to use RNA to turn the CRISPR-Cas9 system on and…
May 4, 2023
Chemistry professor Alexis Komor’s lab designed the Genome Editing Technologies Program as a way to educate high school students on gene-editing technologies and expose them to a possible career in STEM.
May 21, 2024
…the UC San Diego have developed new, efficient genome editing tools called multiplexed orthogonal base editors (MOBEs) to install multiple point mutations at once. Their work, led by Assistant Professor of Chemistry and Biochemistry Alexis Komor’s lab, appears in Nature Biotechnology.
January 3, 2019
UC San Diego researchers have found a stem cell enzyme copy edits more than 20 tumor types, providing new therapeutic target for preventing cancer cell resistance to chemotherapy and radiation.
November 13, 2012
The San Diego Supercomputer Center (SDSC) at the University of California, San Diego, has been recognized by HPCwire, a top online publication covering high-performance computing and related technologies, for the Center’s innovative Data Oasis parallel file storage system.
November 17, 2015
…Diego, is a recipient of this year’s HPCwire and Editors’ Choice Awards for its new Comet supercomputer that entered production earlier this year as a result of a National Science Foundation grant worth nearly $24 million including hardware and operating funds.
